SABER™ Bupivacaine, a novel extended-release formulation of bupivacaine for postoperative pain control demonstrates dose-response, safety and no impact on surgical wound healing following inguinal herniorrhapy. Hadj A, Nicholson D, Moodie J, Turner R, Watts R, Abrouk N, Langecker P, Lissin D. American College of Surgeons 95^th Annual Clinical Congress, October 12, 2009.

SABER™ Formulation for Intra-Articular Delivery of rhGH. Sekar M, Okumo F, van Osdol W, Tamraz W, Tung D, Sverdrup F. The American Association of Pharmaceutical Scientists 2009 National Biotechnology Meeting, June 21-25, 2009.

Clinical Trial Results: A Randomized, Double-Blind, Placebo-Controlled Trial of a Three-Day Bupivacaine Patch (ELADUR™) in Patients with Post-Herpetic Neuralgia. Wallace MS, Kudrow DB, McElveen WA, Drass MJ, Webster LR, Huddlestone JJ, Reynolds LW, Lissin DV, Langecker P. The American Pain Society 27^th Annual Meeting, May 8, 2008.

Post-Operative Pain Control with Extended-Release Bupivacaine Formulation. Clinical Trial Results in Inguinal Hernia Repair. Nicholson D., Brown C., Turner R., Hadj A., Watts R., Shah J., Abrouk N., Lissin D., Langecker P. American Hernia Society, March 15, 2008.

Intracranial drug-delivery scaffolds: Biocompatibility evaluation of sucrose acetate isobutyrate gels. J Lee, GI Jallo, MB Penno, KL Gabrielson, GD Young, RM Johnson, EM Gillis, C Rampersaud, BS Carson, M Guarnieri. Toxicol Appl Pharmacol. 2006, April 19

DUROS® Osmotic Pharmaceutical Systems for Parenteral & Site-Directed Therapy. J. Wright, S. Yum, RM. Johnson Drug Delivery Technology Magazine 2003 Vol 3 No 1: 64-73.

Implantable Osmotic Pump Providing Continuous Subcutaneous Delivery of Sufentanil for Chronic Pain, D. Fisher, Presented at the 2^nd World Congress of World Institute of Pain. June 27-30, 2001; Istanbul, Turkey, Symposium.

Pharmacokinetic Advantage of Intrapericardially Applied Substances in the Rat. J. Hermans, H. Van Essen, H. Struijker-Boudier, R. Johnson, F. Theeuwes, J. Smits. The Journal of Pharmacology and Experimental Therapeutics. 2002; 301: 672-678.

Applications of Continuous Site-Directed Drug Delivery. R. Johnson, A. Verity. Proceedings of the Western Pharmacology Society. 2002; 45: 219-222.

A New Drug Delivery Catheter For Surgically Eloquent Tissue. E. Gillis, M. Guarnieri, B. Carson, P. Storm, R. Clatterbuck, Y. Liu, C. Rampersaud, R. Johnson. Presented at the 2^nd International Symposium on Tumor Targeted Delivery Systems, Sept 2002; A:35.

Designed Experiment for Process Development and Validation of a Novel Biodegradable Polymer, poly(DL-lactide-COOH). T. Williams, H. Maturi, B.S. Watson, J. Middleton, D. Gale. Presented at the AAPS workshop on Critical Issues in the Design and Applications of Polymeric Biomaterials in Drug Delivery, 2002, February 28 – March 1, Arlington, Virginia.

Evaluation of the SABER^TM Delivery System for Sustained Release of Growth Hormone – Formulation Design and In Vivo Assessment. F. Okumu, A. Daugherty, L. Dao, P. Felder, D. Brooks, S. Sane, S.A. Sullivan, A.J. Tipton, J. Cleland. Presented at the 28^th International Symposium of The Controlled Release Society, 2001, June 23-27, San Diego, California.

Zero-Order, 30-Day Release of Analgesics from Coaxial Implants. S. Meador, R. Jefferson, H. Maturi, M. Carraway, J. Gibson, A. Tipton. Presented at the 28^th International Symposium of The Controlled Release Society, 2001, June 23-27, San Diego, California.

In vitro Degradation of Molded Poly(L-lactide) Parts Sterilized by Ethylene Oxide and Gamma Irradiation. J.C. Middleton, P.P. Kines, A.D. Rogers, J.T. Strong. Presented at the Society for Biomaterials Annual Meeting, 2001, April 25-29, St. Paul, Minnesota.

Gels. A.J. Tipton. Presented at the American Association of Pharmaceutical Scientists Workshop: Assuring Quality and Performance of Sustained and Controlled Release Parenterals, 2001, April 19-20, Washington, D.C.

An In Vitro Degradation Study Comparing Poly(DL-lactide-co-glycolide) with Acid End Groups and Ester End Groups. N.M. Erickson, P.P. Kines, S.K. Meador, J.C. Middleton, C.T. Williams, J.C. Williams. Presented at the 20^th Southern Biomedical Engineering Conference, 2001, February 9-11, Birmingham, Alabama.

Drug Delivery from a Controlled Release Aerosol: Effects of Formulation Variables. K.M. Carraway, S.K. Meador, S.A. Sullivan, J.W. Gibson, A.J. Tipton. Presented at the AAPS Annual Meeting and Exposition, 2000, October 29 - November 2, Indianapolis, Indiana.

Synthetic Biodegradable Polymers as Orthopedic Devices. John C. Middleton and Arthur J. Tipton. Biomaterials, 2000, 2335-2346.

In Situ Gelling Systems to Deliver Peptides and Proteins. A.J. Tipton. Presented at the 5^th International Drug Delivery Technologies & Deal-Making Summit and Exposition, 2000, July 26-28, Princeton, New Jersey.

Evaluation of SABER^TM as a Local Delivery System for rhVEGF-Formulation Design and in vitro Assessment. F.W. Okumu, A. Daugherty, S.A. Sullivan, A.J. Tipton, J.L. Cleland. Presented at the 27^th International Meeting of The Controlled Release Society, 2000, July 7-13, Paris, France.

Incorporation of Polymer Microparticles into Sucrose Acetate Isobutyrate Reduces Burst and Extends Release. S.A. Sullivan, S.K. Meador, K.M. Carraway, A.J. Tipton, J.W. Gibson. Presented at the 27^th International Meeting of The Controlled Release Society, 2000, July 7-13, Paris, France.

Effect of Gamma Irradiation on Leuprolide Acetate Release from Polylactide Implants. J.W. Gibson, S.K. Meador, J. Tanglertpaibul, R. Bhardwaj, T.S. Ingallinera, A.J. Tipton. Presented at the 27^th International Meeting of The Controlled Release Society, 2000, July 7-13, Paris, France.

Drug Release from a Novel Controlled Release Aerosol Based on Sucrose Acetate Isobutyrate. K. Michelle Carraway, Stacey A. Sullivan, Stacey K. Meador, Julie C Williams, John W. Gibson, and Arthur J. Tipton. Presented at the AAPS Midwest Regional Meeting. 2000, May 22, Chicago, Illinois.

Long-Term Stability of Poly(DL-lactide) and Poly(DL-lactide-co-glycolide) Under Different Storage Conditions. Todd Williams, Patricia Kines, Craig Martin, and John Middleton. Presented at the Sixth World Biomaterials Congress, 2000, May 15-20, Kamuela, Hawaii.

Local Delivery from a Novel Biodegradable In Situ Delivery System. Arthur J. Tipton, Stacey A. Sullivan, K. Michelle Carraway, Dawn A. Smith, and John W. Gibson. Presented at the Sixth World Biomaterials Congress, 2000, May 15-20, Kamuela, Hawaii.

SABER^TM Provides Burst Free Release of Growth Hormone from PLGA Microspheres. F.W. Okumu, S. Darling, L.N. Dao, P.J. Fielder, S.A. Sullivan, A.J. Tipton, and J.L. Cleland. Presented at the Millennial World Congress of Pharmaceutical Sciences, 2000, April 16-20, San Francisco, California.

Extended Release of Human Growth Hormone Suspended in SABER^TM Formulation Design and In Vitro Assessment. S. Darling, F.W. Okumu, S.A. Sullivan, A.J. Tipton, and J.L. Cleland. Presented at the Millennial World Congress of Pharmaceutical Sciences, 2000, April 16-20, San Francisco, California.

Long Term Stability of Lactide and Glycolide Polymers. C.T. Williams, C.S. Martin, P.P. Kines, and J.C. Williams. Presented at the 19th Southern Biomedical Engineering Conference, 2000, April 14-16, Blacksburg, Virginia.

Depot Delivery of Proteins in the New Millennium: From Microspheres to Injectable Gels. Jeffrey L. Cleland, OluFumni L. Johnson, Susan Darling, Arthur J. Tipton, Gaylen M. Zentner, Stacey Sullivan, John Gibson, and Franklin W. Okumu. Presented at the 6th European Symposium on Controlled Drug Delivery, 2000, April 12, Noordwijk Aan Zee, The Netherlands.

In Situ Gelling Formulations. Arthur J. Tipton and Richard L. Dunn. In: Sustained Release Injectable Products, edited by Judy Senior and Michael Radomsky, Interpharm Press, Inc., Buffalo Grove, Illinois, 2000.

Peptide Delivery from an In Situ Gelling System Based on Sucrose Acetate Isobutyrate. A. J. Tipton. Invited lecture at the AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana.

Sustained Release of Lysozyme from the SABER Delivery System. S.A. Sullivan, S.K. Meador, K.M. Carraway, J.C. Williams, J.W. Gibson, and A.J. Tipton. Presented at the AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana.

Oral Controlled Release of Antiretrovirals using the SABER Delivery System Incorporated into Soft Gelatin Capsules. K.M. Carraway, S.A. Sullivan, J.W. Gibson, and A.J. Tipton. Presented at the AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana.

Effects of Formulation Variables on Controlled Release of Paclitaxel and other Chemotherapeutic Agents from a Novel Delivery System. J.W. Gibson, S.A. Sullivan, K.M. Carraway, and A.J. Tipton. Presented at the AAPS Annual Meeting and Exposition, 1999, November 14-18, New Orleans, Louisiana.

Biodegradable Delivery Systems for Estradiol: Comparison Between Poly(DL-lactide) Microspheres and the SABER Delivery System. C.A. Johnson, D.L. Thompson, Jr., S.A. Sullivan, J.W. Gibson, A.J. Tipton, B.W. Simon, and P.J. Burns. Presented at the 26^th International Meeting of The Controlled Release Society, 1999, June 20-25, Boston, Massachusetts.

Evaluation of the SABER Delivery System for the Controlled Release of Deslorelin: Effect of Dose in Estrogen Primed Ovarectomized Gilts. R. Barb, R. Kraeling, G. Rampacek, D. Thompson, Jr., J. Gibson, S. Sullivan, B. Simon, and P.J. Burns. Presented at the 26^th International International Meeting of The Controlled Release Society, 1999, June 20-25, Boston, Massachusetts.

Induction of Mucosal IgA Specific for SeMF3 of Streptococcus equi with Intranasal Vaccination Using a Sucrose Acetate Isobutyrate Based Delivery System. J. Nally, S. Artiushin, A. Sheoran, J. Timoney, J. Gibson, S. Sullivan, R. Gilley, B. Simon, and P.J. Burns. Presented at the 26^th International Meeting of The Controlled Release Society, 1999, June 20-25, Boston, Massachusetts.

Strategies for Scale-up and Manufacturing Issues. J.W. Gibson. Invited Lecture at the Postsymposium Workshops of the 26^th International Symposium on Controlled Release of Bioactive Materials, 1999, June 24-25, Boston, Massachusetts.

New Delivery – Extension of Existing Products. A.J. Tipton. Invited Lecture at the AAPS Eastern Regional Meeting, 1999, June 10-11, Parsippany, New Jersey.

Long-term Stability of Biodegradable Polymers. C.T. Williams, C.S. Martin, P.P. Kines, R.P. Swaim, D.R. Whitfield, and J.Y.Williams. Presented at the 18^th Annual Southern Biomedical Engineering Conference, 1999, May 21-23, Clemson University, South Carolina.

The Effect of Peg End Groups on the Degradation of a 75/25 Poly(DL-lactide-co-glycolide). John C. Middleton and Julie C. Yarbrough. Presented at the 23^rd Annual Meeting of the Society for Biomaterials Meeting, 1999, April 28 - May 2, Providence, Rhode Island.

In Vitro and In Vivo Evaluation of a Novel In Situ-Forming Parenteral Delivery System. J.W. Gibson, S.A. Sullivan, P.J. Burns, and A.J. Tipton. Poster presented at the meeting of Recent Advances in Drug Delivery Systems, 1999, February 22-25, Salt Lake City, Utah.

Sustained Release of Bupivacaine from the SABER Delivery System. S.A. Sullivan, J. W. Gibson, and A. J. Tipton. Presented at the AAPS Annual Meeting and Exposition, 1998, November 15-19, San Francisco, California.

Effect of Process Variables on the Preparation of Biodegradable Microspheres. Bruce W. Hudson, Lisa M. Moyer, David R. Whitfield, and John W. Gibson. Presented at the AAPS Annual Meeting and Exposition, 1998, November 15-19, San Francisco, California.

Development and Validation of a Stability-Indicating Method for Poly (DL-Lactide) Excipients Used in Injectable Microspheres. S. J. Lawson, K. R. Sims, C. S. Martin, and J. W. Gibson. Presented at the AAPS Annual Meeting and Exposition, 1998, November 15-19, San Francisco, California.

Sustained Release of Orally Administered Active Using SABER^TM Delivery System Incorporated into Soft Gelatin Capsules. S.A. Sullivan, J.C. Yarbrough, R.W. Fengl, A.J. Tipton, and J.W. Gibson. Presented at the 25^th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada.

Pharmacodynamic Evaluation of Biodegradable Estradiol-17b Microspheres and Prostaglandin F2a for the control of Estrus and Ovulation in Gilts. R. Cushman, J.H. Britt, P. Davis, U. Boonyaprakob, V. Hedgpeth, J. Gibson, B. Hudson, and P.J. Burns. Presented at the 25^th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada.

Sustained Release of Progesterone and Estradiol From the SABER ^TM Delivery System: In Vitro and In Vivo Release Rates. S.A. Sullivan, J.W. Gibson, P.J. Burns, L. Franz, E.L. Squires, D.L. Thompson, and A.J. Tipton. Presented at the 25^th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada.

Evaluation of the SABER^TM Delivery System for the Controlled Release of the GnRH Analog Deslorelin for Advancing Ovulation in Mares: Effect of Gamma Radiation. R. Betschart, J. Fleury, E.L. Squires, T. Nett, J. Gibson, S. Sullivan, A. Tipton, and P.J. Burns. Presented at the 25^th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada.

Evaluation of the SABER^TM Delivery System for the Controlled Release of Deslorelin for Advancing Ovulation in the Mare: Effects of Formulation & Dose. J. Fleury,. E.L. Squires, R. Betschart, J. Gibson, S. Sullivan, A. Tipton, and P.J. Burns. Presented at the 25^th International Meeting of The Controlled Release Society, 1998, June 21-26, Las Vegas, Nevada.

Synthetic Biodegradable Polymers as Medical Devices. John C. Middleton and Arthur J. Tipton. Medical Plastics and Biomaterials, 1998, March/April, 31-38. To view this paper, please click here.

Long-Term Stability of Biodegradable Polymers. C.T. Williams, J.C. Middleton, K.R. Sims, R.P. Swaim, D.R. Whitfield, and J.C. Yarbrough. Presented at the 17^th Southern Biomedical Engineering Conference, 1998, February 6-8, San Antonio, Texas.

Drug Delivery from In Situ Formed Depot Systems. A.J. Tipton. Invited Lecture at the 33^rd Annual AAPS Pharmaceutical Technologies Section Arden House Conference, 1998, January 18-23, Harriman, New York.

Delivery of Taxolâ and Other Antineoplastic Agents from a Novel System Based on Sucrose Acetate Isobutyrate. S.A. Sullivan, R.M. Gilley, J.W. Gibson and A.J. Tipton. Pharm. Res., 1997, 14 (11), 291.

Pharmacodynamic Evaluation of the SABER^TM Delivery System for the Controlled Release of the GnRH Analogue Deslorelin Acetate for Advancing Ovulation in Cyclic Mares. P. Burns, D. Thompson, F. Donadue, L. Kincald, B. Leise, J. Gibson, R. Swaim, and A. Tipton. Presented at the 24^th International Meeting of The Controlled Release Society, 1997, June 16-19, Stockholm.

Evaluation of the Saber Delivery System for the Release of GnRH Analog Deslorelin Acetate for Advancing Ovulation in the Mare. F.J. Donadue, D.L. Thompson, P.J. Burns, A.J. Tipton, J.W. Gibson, R.P. Swaim, L.A. Kincald, and B.S. Leise. Presented at the 15^th Annual Meeting of The Equine Nutrition and Physiology Society Meeting, 1997, May 29-31, Fort Worth, Texas.

The Melt Viscosity of Polyglycolic Acid as a Function of Shear Rate, Moisture, and Inherent Viscosity. J.C. Middleton, C.T. Williams, and R.P. Swaim. Presented at the 22^nd Annual Meeting of the Society for Biomaterials, 1997, April 30-May 4, New Orleans, Louisiana.

A Novel Parenteral Delivery System. Dawn Alison Smith and Arthur J. Tipton. Pharm. Res. 1996, 13(9), 300.

Evaluation of a New Continuous Process for Preparation of Progesterone and Estradiol Microspheres: An In Vivo Pharmacokinetics Study. P.J. Burns, T.R. Tice, D. Mason, D. Love, T. Ferrell, J. Gibson, K. Dippert, and E. Squires. The Controlled Release Society, Advances in Controlled Delivery, 1996, August 21-22, Baltimore, Maryland.

Controlled Release of Heparin from Vascular Grafts Over a 55 Day Period. E. Espinal, J. Bulgrin, M. Chapman, S. Schmidt, and A. J. Tipton. American College of Surgeons Meeting, 1995, March 13-16, Akron, Ohio.

Controlled Release of Diclofenac-Na from Cellulose Ester Microspheres. J. A. Nabors, W.K. Hopkins, M.E. Hudson, J. Gibson, D.M. Wyatt, and A.J. Tipton. Pharm. Res. 1994, 11(10), 295.

Influence of Injection Rate on Tensile Strength and Molecular Weight of Molded Poly(L-Lactide)Test Pieces. D.N. Ellis and A.J. Tipton. The 20^th Annual Meeting of the Society for Biomaterials, 1994, April 5-9, Boston, Massachusetts.