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DURECT Corporation Presenting at the BIO CEO and Investor Conference

CUPERTINO, CA-

February 12, 2007

DURECT Corporation (NASDAQ: DRRX) announced today that it will present at the BIO CEO Investor Conference. The conference is being held at The Waldorf Hotel in New York, NY. James E. Brown, DVM, President and CEO, will be presenting at the conference on February 14, 2007 at 2:15 p.m. Eastern Standard Time (11:15 a.m. Pacific Standard Time).

A live audio webcast of the presentation will be available by accessing DURECT’s homepage at http://www.durect.com and clicking “Investor Relations”.

About DURECT Corporation
DURECT Corporation is an emerging specialty pharmaceutical company focused on the development of pharmaceutical systems based on its proprietary drug delivery platform technologies.  The company is developing pharmaceutical systems to deliver the right drug to the right place in the right amount at the right time to treat chronic and episodic diseases and conditions.

SOURCE DURECT Corporation
CONTACT: Schond L. Greenway, Vice President, Investor Relations and
Strategic Planning of DURECT Corporation, +1-408-777-1417

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