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DURECT Corporation Presenting at the 2007 UBS Global Generic and Specialty Pharmaceuticals Conference

Cupertino, California-

May 01, 2007

DURECT Corporation (Nasdaq: DRRX) announced today that it will present at the 2007 UBS Global Generic and Specialty Pharmaceuticals Conference being held at the Grand Hyatt Hotel in New York City. Matthew J. Hogan, Chief Financial Officer, will be presenting at the conference on May 8th at 2:30 p.m. Eastern Time.

To access the audio webcast: Go to www.ibb.ubs.com. Find the Conference link in the middle of the page. Click on the link. Look for the “Webcast” link under the 2007 Global Generic and Specialty Pharmaceuticals Conference.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company developing pharmaceutical systems based on its proprietary drug delivery platform technologies. The Company currently has a number of late-stage pharmaceutical products in development addressing large markets in pain management, with a number of research programs underway targeting chronic disease and other therapeutic areas. For more information, please visit www.durect.com.

SOURCE: DURECT Corporation

CONTACT: Matthew J. Hogan, Chief Financial Officer, +1-408-777-4936

Media Contact:

Feinstein Kean Healthcare
Jeremiah Hall, Senior Vice President, +415 677-2700, jeremiah.hall@fkhealth.com

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