DURECT Corporation Presenting at the First Annual Merriman Curhan Ford & Co. Investor Summit

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CUPERTINO, Calif., Sep 16, 2004 /PRNewswire-FirstCall via COMTEX/ — DURECT Corporation
(Nasdaq: DRRX) announced today that it will present at the First Annual
Merriman Curhan Ford & Co. Investor Summit. The conference is being held at
The Mark Hopkins Hotel in San Francisco, CA. Dr. James E. Brown, President and
Chief Executive Officer, will be presenting at the conference on Monday,
September 20, 2004 at 10:45 a.m. Pacific Time.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

A live audio webcast of the presentation will be available by accessing
DURECT’s homepage at http://www.www.durect.com and clicking “Investor Relations.”

DURECT Corporation (www.www.durect.com) is pioneering the development and
commercialization of pharmaceutical systems for the treatment of chronic
debilitating diseases and enabling biotechnology-based pharmaceutical
products. DURECT’s goal is to deliver the right drug to the right site in the
right amount at the right time.

CONTACT: Schond L. Greenway, Executive Director, Investor Relations and
Strategic Planning of DURECT Corporation
Phone: +1-408-777-1417


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