DURECT Corporation Presenting at the Adams Harkness & Hill Annual Summer Seminar

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CUPERTINO, Calif., Aug. 1 /PRNewswire-FirstCall/ — DURECT Corporation
(Nasdaq: DRRX) announced today that it will present at the Adams, Harkness &
Hill Annual Summer Seminar. The conference is being held at the Boston
Marriott Long Wharf Hotel. James E. Brown, DVM, President and Chief Executive
Officer, will be presenting at the conference on Wednesday, August 3rd at 9:00
a.m. Eastern Time.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

There will be a live webcast of the presentation from the conference. The
webcast will be available on DURECT’s website under the Event Calendar section
of ‘Investor Relations.’ The presentation will also be available for replay on
DURECT’s website for a period of up to 30 days after the conference.

ABOUT DURECT

DURECT Corporation is an emerging specialty pharmaceutical company focused
on the development of pharmaceutical systems based on its proprietary drug
delivery platform technologies that treat chronic debilitating diseases and
enable biotechnology products. These platform technologies include the
SABER(TM) Delivery System (a patented and versatile depot injectable useful
for protein and small molecule delivery), the ORADUR(TM) sustained release
oral gel-cap technology (an oral sustained release technology with several
potential abuse deterrent properties), the DURIN(TM) Biodegradable Implant
(drug-loaded implant system), the TRANSDUR(TM) transdermal technology and the
MICRODUR(TM) Biodegradable Microparticulates (microspheres injectable system).
DURECT also collaborates with pharmaceutical companies to develop and
commercialize proprietary and enhanced pharmaceutical products based on its
technologies. DURECT has five disclosed on-going development programs of which
four are in collaboration with pharmaceutical partners. Additional information
about DURECT is available at www.www.durect.com.

NOTE: SABER(TM), ORADUR(TM), DURIN(TM), TRANSDUR(TM) and MICRODUR(TM) are
trademarks of DURECT Corporation. Other referenced trademarks belong to their
respective owners.

SOURCE  DURECT Corporation
    -0-                             08/01/2005
    /CONTACT:  Schond L. Greenway, Executive Director, IR and Strategic
Planning of DURECT Corporation, +1-408-777-1417/
    /Photo:  NewsCom:  http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO
             AP Archive:  http://photoarchive.ap.org
             PRN Photo Desk, photodesk@prnewswire.com/
    /Web site:  http://www.www.durect.com /
    (DRRX)

CO:  DURECT Corporation
ST:  California
IN:  BIO MTC HEA
SU:  TDS CCA

SF-ND
-- SFM029 --
1928 08/01/2005 06:30 EDT http://www.prnewswire.com
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