DURECT Corporation Invites You to Join Its Fourth Quarter and Year-End 2006 Conference Call on the Web

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CUPERTINO, Calif., Jan. 30 /PRNewswire-FirstCall/ — In conjunction with
DURECT Corporation’s (Nasdaq: DRRX) fourth quarter and year-end 2006 financial
results press release, you are invited to listen to its conference call that
will be broadcast live over the Internet on Thursday, February 8th, 2007 at
4:30 p.m. EST.

(Photo: NewsCom: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

What: DURECT Corporation’s Fourth Quarter and Year-End 2006 Earnings
Conference Call
When: Thursday, February 8th, 2007, 4:30 p.m. EST (1:30 p.m. PST)
Where: www.www.durect.com and click ‘Investor Relations’
Live over the Internet — Simply log on to the Web at the
address listed above.

If you are unable to participate during the live webcast, the call will be
archived on DURECT’s website under Audio Archive in the “Investor Relations”

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company focused
on the development of pharmaceutical systems based on its proprietary drug
delivery platform technologies focused on treating chronic and episodic
diseases and conditions. The Company currently has a number of late-stage
pharmaceutical products in development initially focused on significant unmet
medical needs in pain management, with a number of research programs underway
in a variety of other therapeutic areas. For more information, please visit
www.www.durect.com .

CONTACT: Schond L. Greenway, Vice President, Investor Relations and
Strategic Planning of DURECT Corporation, +1-408-777-1417
Photo: NewsCom: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO
AP Archive: http://photoarchive.ap.org
PRN Photo Desk, photodesk@prnewswire.com
Web site: http://www.www.durect.com

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