DURECT Corporation Invites You to Join Its First Quarter 2007 Earnings Conference Call on the Web

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CUPERTINO, Calif., April 30 /PRNewswire-FirstCall/ — In conjunction with
DURECT Corporation’s (Nasdaq: DRRX) first quarter 2007 financial results press
release, you are invited to listen to the conference call that will be
broadcast live over the Internet on Monday, May 7th 2007 at 4:30 p.m. EDT.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

A live audio webcast of the presentation will be available by accessing
DURECT’s homepage at http://www.www.durect.com and clicking “Investor Relations.”
If you are unable to participate during the live webcast, the call will be
archived on DURECT’s website under Audio Archive in the “Investor Relations”

What: DURECT Corporation’s First Quarter 2007 Earnings Conference Call
When: Monday, May 7th, 2007, 4:30 p.m. EDT (1:30 p.m. PDT)
Where: http://www.www.durect.com and click ‘Investor Relations’ Live over the
Internet — Simply log on to the Web at the address listed above.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company
developing pharmaceutical systems based on its proprietary drug delivery
platform technologies. The Company currently has a number of late-stage
pharmaceutical products in development addressing large markets in pain
management, with a number of research programs underway targeting chronic
disease and other therapeutic areas. For more information, please visit

CONTACT: Matthew J. Hogan, Chief Financial Officer, DURECT Corporation,
+1-408-777-4936; or Jeremiah Hall, Senior Vice President, Feinstein Kean
Healthcare, +1-415-677-2700, or jeremiah.hall@fkhealth.com
Photo: NewsCom: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO
AP Archive: http://photoarchive.ap.org
PRN Photo Desk, photodesk@prnewswire.com
Web site: http://www.www.durect.com

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