DURECT to Present at UBS Global Life Sciences Conference

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CUPERTINO, Calif., Sept. 20 /PRNewswire-FirstCall/– DURECT Corporation
(Nasdaq: DRRX) announced today that James Brown, President and CEO, will
present at the UBS Global Life Sciences Conference in New York on September
27, 2007 at 1:30 p.m. Eastern Time.

A live audio webcast of the presentation will be available by accessing
DURECT’s homepage at http://www.www.durect.com and clicking “Investor Relations.”
If you are unable to participate during the live webcast, the call will be
archived on DURECT’s website under Audio Archive in the “Investor Relations”
section.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company
developing pharmaceutical systems based on its proprietary drug delivery
platform technologies. The Company currently has a number of late-stage
pharmaceutical products in development addressing large markets in pain
management, with a number of research programs underway targeting chronic
disease and other therapeutic areas. For more information, please visit
http://www.www.durect.com.

SOURCE DURECT Corporation

CONTACT: Matthew J. Hogan, Chief Financial Officer of DURECT
Corporation, +1-408-777-4936
Web site: http://www.www.durect.com

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