DURECT Corporation Invites You to Join Its Third Quarter 2007 Earnings Conference Call

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CUPERTINO, Calif., Oct. 30 /PRNewswire-FirstCall/ — In conjunction with
DURECT Corporation’s (Nasdaq: DRRX) third quarter 2007 financial results press
release, you are invited to listen to the conference call that will be
broadcast live over the Internet on Thursday, November 1, 2007 at 4:30 p.m.
EDT (1:30 PM PDT).

    (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO)

    When:   Thursday, November 1, 2007, 4:30 PM EDT (1:30 PM PDT).
    Where:  Live over the Internet - Simply log on to http://www.www.durect.com,
            then click 'Investor Relations' and then 'Events Calendar.'

If you are unable to participate during the live webcast, the call will be
archived on DURECT’s website under Audio Archive in the “Investor Relations”
section.

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company
developing pharmaceutical systems based on its proprietary drug delivery
platform technologies. The Company currently has a number of late-stage
pharmaceutical products in development addressing large markets in pain
management, with a number of research programs underway targeting chronic
disease and other therapeutic areas. For more information, please visit
http://www.www.durect.com.

SOURCE  DURECT Corporation
    -0-                             10/30/2007
    /CONTACT:  Matthew J. Hogan, Chief Financial Officer of DURECT
Corporation, +1-408-777-4936/
    /Photo:  NewsCom:  http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO
             AP Archive:  http://photoarchive.ap.org
             PRN Photo Desk, photodesk@prnewswire.com /
    /Web site:  http://www.www.durect.com /
    (DRRX)

CO:  DURECT Corporation
ST:  California
IN:  HEA MTC
SU:  CCA

BJ-AE
-- AQTU061 --
8699 10/30/2007 09:00 EDT http://www.prnewswire.com
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