DURECT to Host Webcast in Conjunction with an Analyst’s Day on October 17

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CUPERTINO, Calif., Oct. 16 /PRNewswire-FirstCall/ — DURECT Corporation
(Nasdaq: DRRX) announced today that it will be hosting an Analyst Event in New
York on October 17, 2007 at 12:00 p.m. Eastern Time. A live audio webcast of
the presentation will begin at 12:30 p.m. Eastern Time and will be available
by accessing DURECT’s homepage at http://www.www.durect.com and clicking “Investor
Relations”. If you are unable to participate during the live webcast, the
call will be archived on DURECT’s website under Audio Archive in the “Investor
Relations” section.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company
developing pharmaceutical systems based on its proprietary drug delivery
platform technologies. The Company currently has a number of late-stage
pharmaceutical products in development addressing large markets in pain
management, with a number of research programs underway targeting chronic
disease and other therapeutic areas. For more information, please visit

CONTACT: Matthew J. Hogan, Chief Financial Officer of DURECT
Corporation, +1-408-777-4936
Photo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO
AP Archive: http://photoarchive.ap.org
PRN Photo Desk, photodesk@prnewswire.com
PRN Photo Desk, +1-888-776-6555 or +1-212-782-2840
Web site: http://www.www.durect.com

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