DURECT to Present at Upcoming Conferences

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CUPERTINO, Calif., Nov 01, 2007 /PRNewswire-FirstCall via COMTEX News Network/ — DURECT Corporation
(Nasdaq: DRRX) announced today that it will present a corporate overview and
update at two upcoming life sciences conferences in New York, NY.

— CIBC World Markets 18th Annual Healthcare Conference on Monday,
November 5, 2007 at the Waldorf-Astoria Hotel at 1:20 p.m. EST.
— Acumen Biofin Rodman & Renshaw 9th Annual Healthcare Conference on
Tuesday, November 6, 2007 at the New York Palace Hotel at
4:45 p.m. EST.
(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO)

A live audio webcast of the presentation will be available by accessing
DURECT’s homepage at http://www.www.durect.com and clicking “Investor Relations”.
If you are unable to participate during the live webcast, the call will be
archived on DURECT’s website under Audio Archive in the “Investor Relations”

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company
developing pharmaceutical systems based on its proprietary drug delivery
platform technologies. The Company currently has a number of late-stage
pharmaceutical products in development addressing large markets in pain
management, with a number of research programs underway targeting chronic
disease and other therapeutic areas. For more information, please visit



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