DURECT Corporation Presenting at the CIBC World Markets Annual Biotechnology & Specialty Pharmaceuticals Conference

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CUPERTINO, Calif., March 30 /PRNewswire-FirstCall/ — DURECT Corporation
(Nasdaq: DRRX) announced today that it will present at the CIBC World Markets
Annual Biotechnology & Specialty Pharmaceuticals Conference. The conference is
taking place April 4-5th at The Millennium Broadway Hotel in New York City,
New York. James E. Brown, DVM, President and Chief Executive Officer will be
presenting at the conference on Tuesday, April 4th at 10:30 a.m. Eastern Time.

(Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO )

A live audio webcast of the presentation will be available by accessing
DURECT’s homepage at http://www.www.durect.com and clicking “Investor Relations.”

About DURECT Corporation

DURECT Corporation is an emerging specialty pharmaceutical company focused
on the development of pharmaceutical systems based on its proprietary drug
delivery platform technologies. The company is developing pharmaceutical
systems to deliver the right drug to the right place in the right amount at
the right time to treat chronic and episodic diseases and conditions.

SOURCE:
DURECT Corporation
03/30/2006

CONTACT:
Schond L. Greenway, Vice President, Investor Relations and
Strategic Planning of DURECT Corporation, +1-408-777-1417

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