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DURECT Corporation Invites You to Join Its Third Quarter 2007 Earnings Conference Call

CUPERTINO, Calif., Oct. 30 /PRNewswire-FirstCall/ — In conjunction with DURECT Corporation’s (Nasdaq: DRRX) third quarter 2007 financial results press release, you are invited to listen to the conference call that will be broadcast live over the Internet on Thursday, November 1, 2007 at 4:30 p.m. EDT (1:30 PM PDT). (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO) When: Thursday, November 1,

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DURECT to Host Webcast in Conjunction with an Analyst’s Day on October 17

CUPERTINO, Calif., Oct. 16 /PRNewswire-FirstCall/ — DURECT Corporation (Nasdaq: DRRX) announced today that it will be hosting an Analyst Event in New York on October 17, 2007 at 12:00 p.m. Eastern Time. A live audio webcast of the presentation will begin at 12:30 p.m. Eastern Time and will be available by accessing DURECT’s homepage at

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DURECT to Present at 2007 BIO Investor Forum

CUPERTINO, Calif., Oct. 4 /PRNewswire-FirstCall/ — DURECT Corporation (Nasdaq: DRRX) announced today that James E. Brown, President and CEO, will be presenting at the 2007 BIO Investor Forum to be held at the Palace Hotel in San Francisco on October 11, 2007 at 10:30 a.m. Pacific Time. (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO) A live audio webcast of the

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DURECT to Present at UBS Global Life Sciences Conference

CUPERTINO, Calif., Sept. 20 /PRNewswire-FirstCall/– DURECT Corporation (Nasdaq: DRRX) announced today that James Brown, President and CEO, will present at the UBS Global Life Sciences Conference in New York on September 27, 2007 at 1:30 p.m. Eastern Time. A live audio webcast of the presentation will be available by accessing DURECT’s homepage at http://www.www.durect.com and

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DURECT to Present at Merriman Curhan Ford’s Annual Investor Summit

CUPERTINO, Calif., Sept. 11 /PRNewswire-FirstCall/ — DURECT Corporation (Nasdaq: DRRX) announced today that Felix Theeuwes, Chairman and CSO, will present at the 4th annual Merriman Curhan Ford & Co. Investor Summit on September 17, 2007 at 11:45 a.m. Pacific Time. This event will be held at the Mark Hopkins InterContinental Hotel in San Francisco. More

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DURECT Corporation to Present at the NewsMakers in the Biotech Industry Investment Conference

CUPERTINO, Calif., Aug. 29 /PRNewswire-FirstCall/ — DURECT Corporation (Nasdaq: DRRX) announced today that James E. Brown, President and CEO, will be presenting at the NewsMakers in the Biotech Industry Investment Conference to be held in New York City on September 6, 2007 at 11:30 a.m. Eastern Time. (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO) A live audio webcast of the

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DURECT Corporation Announces Second Quarter 2007 Financial Results

CUPERTINO, Calif., Aug 07, 2007 /PRNewswire-FirstCall via COMTEX News Network/ — DURECT Corporation (Nasdaq: DRRX) announced today financial results for the three months ended June 30, 2007. Total revenues were $13.4 million for the three months ended June 30, 2007, compared to $6.1 million for the same period in 2006; revenues in the second quarter

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DURECT Corporation Invites You to Join Its Second Quarter 2007 Earnings Conference Call on the Web

CUPERTINO, Calif., July 31, 2007 /PRNewswire-FirstCall via COMTEX News Network/ — In conjunction with DURECT Corporation’s (Nasdaq: DRRX) second quarter 2007 financial results press release, you are invited to listen to the conference call that will be broadcast live over the Internet on Tuesday, August 7th 2007 at 4:30 p.m. EDT. (Logo: http://www.newscom.com/cgi-bin/prnh/20020717/DRRXLOGO ) A

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DURECT Reports Positive Results from POSIDUR(TM) Phase IIb Hernia Trial, Triggering $8 million Milestone Payment from Nycomed

Phase IIb Trial Achieves Statistically Significant Reductions in Pain and Total Consumption of Supplemental Opioid Analgesic Medications Versus Placebo CUPERTINO, Calif., July 17 /PRNewswire-FirstCall/ — DURECT Corporation (Nasdaq: DRRX) announced today positive results from a 122 patient Phase IIb clinical trial of POSIDUR(TM) for treatment of post-operative pain in patients undergoing inguinal hernia repair. This

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